Metabolic responses of body to stress and starvation

The human body like other animals behave differently towards stress and starvation. Here is the summary of the physiological and Metabolic responses of body to stress and starvation (absence of nutrition)

The metabolic response to starvation

The first metabolic response to starvation is that the body switch from carbohydrate metabolism to that of fat catabolism, in the context of a hypometabolic state, with minimized catabolism.

Initially, the precursors of carbohydrate stores (eg. glycogen) are depleted.

Then, during the first 24–48 hours there is enhanced gluconeogenesis in the body from amino acids and glycerol.

Subsequently, after 48 hours ketogenesis takes over, and most of the metabolic needs of body are met by ketone bodies and free fatty acids.

Consequently there is decrease level of insulin levels, and relatively increased influence from catecholamines and cortisol.

Over prolonged starvation of many days, protein catabolism start , which result in the degradation of structurally important proteins leading to organ system dysfunction.

The metabolic response to stress

The metabolic response to stress is somehow different from that of starvation. The metabolic response in stress is mediated by some important catabolic hormones (e.g. glucagon, catecholamines and corticoids) kindly read full article https://bit.ly/3OduYCx